A Rare Case of a Rectal Gastrointestinal Stromal Tumor (GIST) Discovered During a Routine Colonoscopy

نویسندگان

چکیده

A gastrointestinal stromal tumor (GIST) is a rare malignancy, accounting for only 0.1% to 3% of all (GI) malignancies. Although GISTs are the most common mesenchymal GI tract, they primarily found within stomach, with rectal rarely reported. They may present bleeding, constipation, pain, or palpable mass while some incidentally. The incidence has been on rise, possibly due advancements in diagnostic technology. In this case report, we 50-year-old female who presented intermittent constipation and pain was have submucosal during routine colonoscopy. Further evaluation confirmed presence spindle-cell neoplasm, which mildly cellular showed positive expression CD34 CD117 immunohistochemistry, consistent diagnosis GIST rectum. This report emphasizes importance colonoscopies early detection neoplastic lesions colon highlights GISTs, their risk factors, pathogenesis, sites occurrence.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

pancreatic metastasis from rectal gastrointestinal stromal tumor: a case report

gastrointestinal stromal tumors are mesenchymal neoplasms of the gastrointesti- nal tract that originate from all areas of the gastrointestinal tract. metastases to the liver, peritoneum, bones, lungs and soft tissues have been reported. we present the case of a 47- year-old woman with rectal gastrointestinal stromal tumor that underwent wide local excision. she was treated with imatinib for a ...

متن کامل

Gastrointestinal stromal tumor (GIST).

Gastrointestinal stromal tumors (GISTs) may be defined as morphologically spindle cell, epithelioid, or occasionally pleomorphic mesenchymal tumours of the gastrointestinal tract that usually express the KIT protein and harbour mutation of a gene that encodes for a type III receptor tyrosine kinase (either KIT or PDGFRA). In Caucasian populations their annual incidence is 10 to 15 cases per mil...

متن کامل

A rare ovarian tumor, leydig stromal cell tumor, presenting with virilization: a case report

 Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis ...

متن کامل

Sclerosing Stromal Tumor: A Rare Ovarian Neoplasm

Ovarian sex cord-stromal tumors are relatively infrequent neoplasms that account for approximately 8% of all primary ovarian neoplasm. Sex cord-stromal tumors of the ovary include granulosa cell tumors, fibrothecomas, Sertoli-Leydigcell tumors, steroid cell tumors, and sclerosing stromal tumors (SST). Sclerosing stromal tumors account for 2% to 6% of ovarian stromal tumors. Despite the rarity o...

متن کامل

Desmin expression by a gastrointestinal stromal tumor in a dog

This report describes the histological and immunohistochemical features of a small intestinal tumor that resembled a human gastrointestinal stromal tumor (GISTs) in a seven-year-old male cross-breed dog. This was unique because of the expression of desmin by the tumor. Grossly, the white-gray tumor measured 8.0 × 4.0 × 6.5 cm and was 760 gram in weight. It was cystic and enveloped the jejunum. ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Cureus

سال: 2023

ISSN: ['2168-8184']

DOI: https://doi.org/10.7759/cureus.41030